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Breast Cancer is the most common tumor in women and it is the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland had greatly increased over the last decade. In Breast Cancer in the Post Genomic Era, Antonio Giordano, Nicola Normanno, and a panel of international authorities in their field provide a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma. The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment. Additional chapters cover the use of transgenic mice to model human breast cancer and the role of the EGF-CFC family in mammary gland development and neoplasia. Breast Cancer in the Post Genomic-Era succeeds in looking at breast cancer pathogenesis, diagnosis, and treatment under a more comprehensive light, and is a valuable resource for any Radiation or Surgical Oncologist, Cancer Biologist or Pathologist.

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The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.

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Alternative medicine is defined as a treatment modality used in place of conventional medicine. By definition, alternative treatments are not integrated as part of conventional medicine. Complementary medicine, however, makes use of non-conventional treatment modalities, some of which have known efficacy, in combination with conventional treatment. Both alternative and complementary medicine focus on treatment modalities. Integrative medicine, on the other hand, is not about specific non-conventional treatment modalities, but is an approach to treating patients. It strives to integrate the best of complementary and conventional modalities using a multidisciplinary approach through integrative services. This book outlines integrative medicine programs at five leading National Cancer Institute Comprehensive Cancer Centers (The University of Texas M. D. Anderson Cancer Center, Memorial Sloan Kettering Cancer Center, Dana Farber Cancer Institute, The Johns Hopkins Kimmel Oncology Center, and the Mayo Clinic). The focus is on how these centers started their programs, what they are currently doing, and recommendations for starting integrative medicine clinics.

  Specialty: This important book fills a need in the developing area of Pain Medicine, providing physicians with an up-to-date resource that would detail the current understanding about the basic science underlying the mechanism of action of the various CAM therapies

  Specialty: This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs.

Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.